Izzy and George will both be quitting the show... so no, you won't see any more of Izzy, Denny or George after this season... it's really too bad. I loved them all. I wish we could keep them all, especially George... he's a sweetheart.  I think they will probably have him quit to take care of Izzy, or just go away for a while.  Throughout the whole process, Derek will come back and try to help Izzy because he is a loving and caring man... although it has to be said... I'm not impressed with the way Meredith said she wouldn't love him if he wasn't a surgeon... while I get what they were trying to do, it could have been done better... something like I will always love you, but I don't think I would respect you for ignoring your gift. She was cold.   I was not nuts about the storyline for the residents, didn't seem relevant... and really, who cares? (boy, I sound like Cristina here)  Anyhow... I can hardly wait for the next show!!